F2R protein (Oryctolagus cuniculus) - STRING interaction network

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADORA2B	F2R	ENSOCUP00000023252	ENSOCUP00000020419	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	0.870
ADORA2B	GNB3	ENSOCUP00000023252	ENSOCUP00000011129	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.888
ADORA2B	GNB5	ENSOCUP00000023252	ENSOCUP00000010220	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.887
ADORA2B	GNG12	ENSOCUP00000023252	ENSOCUP00000020657	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.880
ADORA2B	LPAR2	ENSOCUP00000023252	ENSOCUP00000010673	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.856
CTSG	F2R	ENSOCUP00000001158	ENSOCUP00000020419	Cathepsin G.	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	0.900
CTSG	PLG	ENSOCUP00000001158	ENSOCUP00000001518	Cathepsin G.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.424
F2R	ADORA2B	ENSOCUP00000020419	ENSOCUP00000023252	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family.	0.870
F2R	CTSG	ENSOCUP00000020419	ENSOCUP00000001158	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Cathepsin G.	0.900
F2R	GNA12	ENSOCUP00000020419	ENSOCUP00000001272	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 12.	0.920
F2R	GNA13	ENSOCUP00000020419	ENSOCUP00000006607	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha 13.	0.939
F2R	GNB3	ENSOCUP00000020419	ENSOCUP00000011129	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.889
F2R	GNB5	ENSOCUP00000020419	ENSOCUP00000010220	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.880
F2R	GNG12	ENSOCUP00000020419	ENSOCUP00000020657	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.875
F2R	LPAR2	ENSOCUP00000020419	ENSOCUP00000010673	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.896
F2R	PLG	ENSOCUP00000020419	ENSOCUP00000001518	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.909
F2R	PROCR	ENSOCUP00000020419	ENSOCUP00000014266	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	Protein C receptor.	0.940
GNA12	F2R	ENSOCUP00000001272	ENSOCUP00000020419	G protein subunit alpha 12.	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	0.920
GNA12	GNA13	ENSOCUP00000001272	ENSOCUP00000006607	G protein subunit alpha 12.	G protein subunit alpha 13.	0.998
GNA12	GNB3	ENSOCUP00000001272	ENSOCUP00000011129	G protein subunit alpha 12.	G protein subunit beta 3.	0.904