INS protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	EGFR	ENSOCUP00000014095	ENSOCUP00000009041	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	GCG	ENSOCUP00000014095	ENSOCUP00000019727	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.432
EGF	IGF1R	ENSOCUP00000014095	ENSOCUP00000012731	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.946
EGF	INS	ENSOCUP00000014095	ENSOCUP00000020463	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.994
EGF	INSR	ENSOCUP00000014095	ENSOCUP00000042281	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.940
EGF	INSRR	ENSOCUP00000014095	ENSOCUP00000009205	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Tyrosine-protein kinase receptor.	0.855
EGF	IRS1	ENSOCUP00000014095	ENSOCUP00000006209	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Insulin receptor substrate 1.	0.502
EGFR	EGF	ENSOCUP00000009041	ENSOCUP00000014095	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	IGF1R	ENSOCUP00000009041	ENSOCUP00000012731	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.964
EGFR	INS	ENSOCUP00000009041	ENSOCUP00000020463	Receptor protein-tyrosine kinase.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.960
EGFR	INSR	ENSOCUP00000009041	ENSOCUP00000042281	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.837
EGFR	INSRR	ENSOCUP00000009041	ENSOCUP00000009205	Receptor protein-tyrosine kinase.	Tyrosine-protein kinase receptor.	0.546
EGFR	IRS1	ENSOCUP00000009041	ENSOCUP00000006209	Receptor protein-tyrosine kinase.	Insulin receptor substrate 1.	0.874
EGFR	LOC100339305	ENSOCUP00000009041	ENSOCUP00000030706	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.807
GCG	EGF	ENSOCUP00000019727	ENSOCUP00000014095	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.432
GCG	GHRL	ENSOCUP00000019727	ENSOCUP00000029787	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Uncharacterized protein.	0.950
GCG	IDE	ENSOCUP00000019727	ENSOCUP00000030432	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Insulin degrading enzyme; Belongs to the peptidase M16 family.	0.886
GCG	INS	ENSOCUP00000019727	ENSOCUP00000020463	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.962
GCG	INSR	ENSOCUP00000019727	ENSOCUP00000042281	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Tyrosine-protein kinase receptor.	0.724
GCG	IRS1	ENSOCUP00000019727	ENSOCUP00000006209	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Insulin receptor substrate 1.	0.615