| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AQP11 | AQP2 | ENSOCUP00000043459 | ENSOCUP00000047709 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.803 |
| AQP11 | AQP7 | ENSOCUP00000043459 | ENSOCUP00000040132 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.956 |
| AQP11 | SLC12A1 | ENSOCUP00000043459 | ENSOCUP00000014189 | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. Belongs to the SLC12A transporter family. | 0.471 |
| AQP2 | AQP11 | ENSOCUP00000047709 | ENSOCUP00000043459 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.803 |
| AQP2 | AQP7 | ENSOCUP00000047709 | ENSOCUP00000040132 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.739 |
| AQP2 | AVPR2 | ENSOCUP00000047709 | ENSOCUP00000032438 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.924 |
| AQP2 | PRKACB | ENSOCUP00000047709 | ENSOCUP00000043583 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.821 |
| AQP2 | REN | ENSOCUP00000047709 | ENSOCUP00000017597 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Renin; Belongs to the peptidase A1 family. | 0.764 |
| AQP2 | SLC12A1 | ENSOCUP00000047709 | ENSOCUP00000014189 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. Belongs to the SLC12A transporter family. | 0.872 |
| AQP2 | SLC14A1 | ENSOCUP00000047709 | ENSOCUP00000005841 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Urea transporter; Belongs to the urea transporter family. | 0.819 |
| AQP2 | SLC26A4 | ENSOCUP00000047709 | ENSOCUP00000049992 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. | 0.734 |
| AQP2 | SLC9A3 | ENSOCUP00000047709 | ENSOCUP00000046707 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Sodium/hydrogen exchanger 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. | 0.723 |
| AQP2 | UMOD | ENSOCUP00000047709 | ENSOCUP00000033735 | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uromodulin. | 0.880 |
| AQP7 | AQP11 | ENSOCUP00000040132 | ENSOCUP00000043459 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. | 0.956 |
| AQP7 | AQP2 | ENSOCUP00000040132 | ENSOCUP00000047709 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.739 |
| AQP7 | AVPR2 | ENSOCUP00000040132 | ENSOCUP00000032438 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | 0.430 |
| AQP7 | SLC9A3 | ENSOCUP00000040132 | ENSOCUP00000046707 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Sodium/hydrogen exchanger 3; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. | 0.458 |
| AVPR2 | AQP2 | ENSOCUP00000032438 | ENSOCUP00000047709 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Aquaporin-2; Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.924 |
| AVPR2 | AQP7 | ENSOCUP00000032438 | ENSOCUP00000040132 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. | 0.430 |
| AVPR2 | PRKACB | ENSOCUP00000032438 | ENSOCUP00000043583 | Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.489 |