MPLKIP protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MPLKIP

M-phase specific PLK1 interacting protein. (179 aa)

Predicted Functional Partners:

RNF113A

0.846

LRRC42

0.747

PBDC1

0.707

GTF2H5

0.704

SUGCT

0.631

AKIRIN1

0.567

GTF2E2

0.559

ERCC3

0.552

ERCC4

0.551

BIVM

0.548

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKIRIN1	MPLKIP	ENSOCUP00000004769	ENSOCUP00000022276	Uncharacterized protein.	M-phase specific PLK1 interacting protein.	0.567
BIVM	ERCC3	ENSOCUP00000010688	ENSOCUP00000001942	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.995
BIVM	ERCC4	ENSOCUP00000010688	ENSOCUP00000012874	Uncharacterized protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.984
BIVM	GTF2H5	ENSOCUP00000010688	ENSOCUP00000024773	Uncharacterized protein.	General transcription factor IIH subunit 5.	0.844
BIVM	MPLKIP	ENSOCUP00000010688	ENSOCUP00000022276	Uncharacterized protein.	M-phase specific PLK1 interacting protein.	0.548
BIVM	RNF113A	ENSOCUP00000010688	ENSOCUP00000017305	Uncharacterized protein.	Ring finger protein 113A.	0.540
ERCC3	BIVM	ENSOCUP00000001942	ENSOCUP00000010688	ERCC excision repair 3, TFIIH core complex helicase subunit.	Uncharacterized protein.	0.995
ERCC3	ERCC4	ENSOCUP00000001942	ENSOCUP00000012874	ERCC excision repair 3, TFIIH core complex helicase subunit.	ERCC excision repair 4, endonuclease catalytic subunit.	0.975
ERCC3	GTF2E2	ENSOCUP00000001942	ENSOCUP00000013764	ERCC excision repair 3, TFIIH core complex helicase subunit.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.999
ERCC3	GTF2H5	ENSOCUP00000001942	ENSOCUP00000024773	ERCC excision repair 3, TFIIH core complex helicase subunit.	General transcription factor IIH subunit 5.	0.999
ERCC3	MPLKIP	ENSOCUP00000001942	ENSOCUP00000022276	ERCC excision repair 3, TFIIH core complex helicase subunit.	M-phase specific PLK1 interacting protein.	0.552
ERCC3	RNF113A	ENSOCUP00000001942	ENSOCUP00000017305	ERCC excision repair 3, TFIIH core complex helicase subunit.	Ring finger protein 113A.	0.563
ERCC4	BIVM	ENSOCUP00000012874	ENSOCUP00000010688	ERCC excision repair 4, endonuclease catalytic subunit.	Uncharacterized protein.	0.984
ERCC4	ERCC3	ENSOCUP00000012874	ENSOCUP00000001942	ERCC excision repair 4, endonuclease catalytic subunit.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.975
ERCC4	GTF2H5	ENSOCUP00000012874	ENSOCUP00000024773	ERCC excision repair 4, endonuclease catalytic subunit.	General transcription factor IIH subunit 5.	0.771
ERCC4	MPLKIP	ENSOCUP00000012874	ENSOCUP00000022276	ERCC excision repair 4, endonuclease catalytic subunit.	M-phase specific PLK1 interacting protein.	0.551
ERCC4	RNF113A	ENSOCUP00000012874	ENSOCUP00000017305	ERCC excision repair 4, endonuclease catalytic subunit.	Ring finger protein 113A.	0.573
GTF2E2	ERCC3	ENSOCUP00000013764	ENSOCUP00000001942	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.999
GTF2E2	GTF2H5	ENSOCUP00000013764	ENSOCUP00000024773	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	General transcription factor IIH subunit 5.	0.939
GTF2E2	MPLKIP	ENSOCUP00000013764	ENSOCUP00000022276	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	M-phase specific PLK1 interacting protein.	0.559