node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTA1 | KBTBD13 | ENSOCUP00000003527 | ENSOCUP00000023708 | Actin, alpha skeletal muscle. | Kelch repeat and BTB domain containing 13. | 0.741 |
ACTA1 | LMOD3 | ENSOCUP00000003527 | ENSOCUP00000007075 | Actin, alpha skeletal muscle. | Leiomodin 3. | 0.648 |
ACTA1 | MYH11 | ENSOCUP00000003527 | ENSOCUP00000024188 | Actin, alpha skeletal muscle. | Myosin-11; Muscle contraction. | 0.456 |
ACTA1 | MYL1 | ENSOCUP00000003527 | ENSOCUP00000038248 | Actin, alpha skeletal muscle. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.620 |
ACTA1 | NEB | ENSOCUP00000003527 | ENSOCUP00000048133 | Actin, alpha skeletal muscle. | Nebulin. | 0.701 |
ACTA1 | TNNI1 | ENSOCUP00000003527 | ENSOCUP00000008977 | Actin, alpha skeletal muscle. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.666 |
ACTA1 | TNNT2 | ENSOCUP00000003527 | ENSOCUP00000018870 | Actin, alpha skeletal muscle. | Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.532 |
ACTA1 | TNNT3 | ENSOCUP00000003527 | ENSOCUP00000001509 | Actin, alpha skeletal muscle. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.803 |
ACTA1 | TPM2 | ENSOCUP00000003527 | ENSOCUP00000039817 | Actin, alpha skeletal muscle. | Tropomyosin beta chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. | 0.812 |
ACTC1 | KBTBD13 | ENSOCUP00000006542 | ENSOCUP00000023708 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Kelch repeat and BTB domain containing 13. | 0.698 |
ACTC1 | LMOD3 | ENSOCUP00000006542 | ENSOCUP00000007075 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Leiomodin 3. | 0.822 |
ACTC1 | MYH11 | ENSOCUP00000006542 | ENSOCUP00000024188 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin-11; Muscle contraction. | 0.686 |
ACTC1 | MYL1 | ENSOCUP00000006542 | ENSOCUP00000038248 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.940 |
ACTC1 | NEB | ENSOCUP00000006542 | ENSOCUP00000048133 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Nebulin. | 0.639 |
ACTC1 | TNNI1 | ENSOCUP00000006542 | ENSOCUP00000008977 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.732 |
ACTC1 | TNNT2 | ENSOCUP00000006542 | ENSOCUP00000018870 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.986 |
ACTC1 | TNNT3 | ENSOCUP00000006542 | ENSOCUP00000001509 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.795 |
ACTC1 | TPM2 | ENSOCUP00000006542 | ENSOCUP00000039817 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Tropomyosin beta chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. | 0.983 |
KBTBD13 | ACTA1 | ENSOCUP00000023708 | ENSOCUP00000003527 | Kelch repeat and BTB domain containing 13. | Actin, alpha skeletal muscle. | 0.741 |
KBTBD13 | ACTC1 | ENSOCUP00000023708 | ENSOCUP00000006542 | Kelch repeat and BTB domain containing 13. | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.698 |