STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VAV1Vav guanine nucleotide exchange factor 1. (681 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
0.997
SYK
Tyrosine-protein kinase.
   
 0.989
ZAP70
Tyrosine-protein kinase.
   
 0.981
LCP2
Lymphocyte cytosolic protein 2.
   
 0.966
CDC42-2
Uncharacterized protein.
   
 0.957
CDC42
Uncharacterized protein.
   
 0.957
CBL
Cbl proto-oncogene.
    
 0.949
ITK
Tyrosine-protein kinase.
   
 0.936
CD19
CD19 molecule.
   
 0.933
RAC2
Rac family small GTPase 2.
   
 0.928
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.