node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACOT6 | SULT3A1 | ENSOCUP00000026213 | ENSOCUP00000022723 | Acyl-CoA thioesterase 6. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.535 |
FMO3 | LOC100350836 | ENSOCUP00000003129 | ENSOCUP00000024685 | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.553 |
FMO3 | SULT3A1 | ENSOCUP00000003129 | ENSOCUP00000022723 | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.465 |
HARBI1 | SULT3A1 | ENSOCUP00000013863 | ENSOCUP00000022723 | Harbinger transposase derived 1. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.651 |
LOC100350836 | FMO3 | ENSOCUP00000024685 | ENSOCUP00000003129 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | 0.553 |
LOC100350836 | SULT3A1 | ENSOCUP00000024685 | ENSOCUP00000022723 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.428 |
LOC100350836 | SULT4A1 | ENSOCUP00000024685 | ENSOCUP00000020739 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.567 |
LOC100350836 | SULT6B1 | ENSOCUP00000024685 | ENSOCUP00000006247 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.513 |
MCP2 | SULT3A1 | ENSOCUP00000027402 | ENSOCUP00000022723 | Corticostatin-4; This peptide has antibiotic, anti-fungi and antiviral activity. It also inhibits corticotropin (ACTH) stimulated corticosterone production; Belongs to the alpha-defensin family. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.548 |
RSPH4A | SULT3A1 | ENSOCUP00000027076 | ENSOCUP00000022723 | Radial spoke head component 4A. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.426 |
SULT1C2 | SULT3A1 | ENSOCUP00000014015 | ENSOCUP00000022723 | Sulfotransferase 1C2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. Shows activity towards p-nitrophenol. Probably the major stomach sulfotransferase. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.460 |
SULT1C2 | SULT4A1 | ENSOCUP00000014015 | ENSOCUP00000020739 | Sulfotransferase 1C2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. Shows activity towards p-nitrophenol. Probably the major stomach sulfotransferase. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.658 |
SULT1C2 | SULT6B1 | ENSOCUP00000014015 | ENSOCUP00000006247 | Sulfotransferase 1C2; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. Shows activity towards p-nitrophenol. Probably the major stomach sulfotransferase. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.531 |
SULT1E1 | SULT3A1 | ENSOCUP00000004352 | ENSOCUP00000022723 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | 0.433 |
SULT1E1 | SULT4A1 | ENSOCUP00000004352 | ENSOCUP00000020739 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.550 |
SULT1E1 | SULT6B1 | ENSOCUP00000004352 | ENSOCUP00000006247 | Sulfotransferase; Belongs to the sulfotransferase 1 family. | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.482 |
SULT3A1 | ACOT6 | ENSOCUP00000022723 | ENSOCUP00000026213 | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | Acyl-CoA thioesterase 6. | 0.535 |
SULT3A1 | FMO3 | ENSOCUP00000022723 | ENSOCUP00000003129 | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | 0.465 |
SULT3A1 | HARBI1 | ENSOCUP00000022723 | ENSOCUP00000013863 | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | Harbinger transposase derived 1. | 0.651 |
SULT3A1 | LOC100350836 | ENSOCUP00000022723 | ENSOCUP00000024685 | Amine sulfotransferase; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the N-sulfonation of amines (PTHP, aniline, 4-chloroaniline, 2-naphthylamine). | Sulfotransferase; Belongs to the sulfotransferase 1 family. | 0.428 |