STRINGSTRING
SNCA protein (Oryctolagus cuniculus) - STRING interaction network
"SNCA" - Alpha-synuclein in Oryctolagus cuniculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNCAAlpha-synuclein; Synuclein, alpha (non A4 component of amyloid precursor); Belongs to the synuclein family (140 aa)    
Predicted Functional Partners:
LRRK2
Leucine-rich repeat kinase 2 (2527 aa)
     
 
  0.963
PINK1
PTEN induced putative kinase 1 (546 aa)
     
 
  0.899
PARK7
Parkinsonism associated deglycase; Parkinson protein 7 (189 aa)
       
 
  0.879
SNCAIP
Synuclein, alpha interacting protein (968 aa)
       
 
  0.863
APP
Amyloid-beta A4 protein; Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O) (769 aa)
     
 
  0.819
PARK2
Uncharacterized protein (80 aa)
       
 
  0.808
MAPT
Microtubule-associated protein tau (822 aa)
     
 
  0.770
HTT
Huntingtin (3089 aa)
       
 
  0.764
ATP13A2
ATPase type 13A2 (667 aa)
           
  0.758
ENSOCUG00000024058
Uncharacterized protein; Transporter (313 aa)
     
 
  0.717
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, Oryctolagus cuniculus, domestic rabbit, rabbit, rabbits
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