STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADORA2BAdenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family. (444 aa)    
Predicted Functional Partners:
GNAS
GNAS complex locus.
    
 0.961
ADORA2A
Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.
    
0.953
GNAQ
G protein subunit alpha q.
    
 0.927
P2RY1
Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family.
    
 0.926
LOC100346323
Uncharacterized protein.
    
  0.915
FPR1
fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity).
     
 0.910
F2R
Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.
    
0.909
LPAR3
Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.
   
 
 
0.904
LPAR5
Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family.
     
 0.901
LPAR1
Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
0.900
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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