RHOH protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGDIB	ITSN2	ENSOCUP00000005200	ENSOCUP00000019448	Rho GDP dissociation inhibitor beta.	Intersectin 2.	0.476
ARHGDIB	RHOA	ENSOCUP00000005200	ENSOCUP00000011466	Rho GDP dissociation inhibitor beta.	Ras homolog family member A.	0.986
ARHGDIB	RHOB	ENSOCUP00000005200	ENSOCUP00000037384	Rho GDP dissociation inhibitor beta.	Ras homolog family member B.	0.950
ARHGDIB	RHOF	ENSOCUP00000005200	ENSOCUP00000018702	Rho GDP dissociation inhibitor beta.	Ras homolog family member F, filopodia associated.	0.672
ARHGDIB	RHOH	ENSOCUP00000005200	ENSOCUP00000023639	Rho GDP dissociation inhibitor beta.	Ras homolog family member H.	0.911
FAM91A1	MTR	ENSOCUP00000010150	ENSOCUP00000008420	Family with sequence similarity 91 member A1.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.620
FAM91A1	PAK2	ENSOCUP00000010150	ENSOCUP00000007111	Family with sequence similarity 91 member A1.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.647
FAM91A1	RHOH	ENSOCUP00000010150	ENSOCUP00000023639	Family with sequence similarity 91 member A1.	Ras homolog family member H.	0.757
FAM91A1	ROCK1	ENSOCUP00000010150	ENSOCUP00000034408	Family with sequence similarity 91 member A1.	Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity (By similarity). Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A (By similarity). Phosphorylates FHOD1 and acts synergistically with it to promote SRC- dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 [...]	0.541
FAM91A1	ZAP70	ENSOCUP00000010150	ENSOCUP00000005043	Family with sequence similarity 91 member A1.	Tyrosine-protein kinase.	0.507
ITSN2	ARHGDIB	ENSOCUP00000019448	ENSOCUP00000005200	Intersectin 2.	Rho GDP dissociation inhibitor beta.	0.476
ITSN2	PAK2	ENSOCUP00000019448	ENSOCUP00000007111	Intersectin 2.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.495
ITSN2	RHOA	ENSOCUP00000019448	ENSOCUP00000011466	Intersectin 2.	Ras homolog family member A.	0.891
ITSN2	RHOB	ENSOCUP00000019448	ENSOCUP00000037384	Intersectin 2.	Ras homolog family member B.	0.835
ITSN2	RHOF	ENSOCUP00000019448	ENSOCUP00000018702	Intersectin 2.	Ras homolog family member F, filopodia associated.	0.835
ITSN2	RHOH	ENSOCUP00000019448	ENSOCUP00000023639	Intersectin 2.	Ras homolog family member H.	0.835
ITSN2	ROCK1	ENSOCUP00000019448	ENSOCUP00000034408	Intersectin 2.	Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity (By similarity). Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A (By similarity). Phosphorylates FHOD1 and acts synergistically with it to promote SRC- dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 [...]	0.479
ITSN2	ZAP70	ENSOCUP00000019448	ENSOCUP00000005043	Intersectin 2.	Tyrosine-protein kinase.	0.509
MTR	FAM91A1	ENSOCUP00000008420	ENSOCUP00000010150	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Family with sequence similarity 91 member A1.	0.620
MTR	PAK2	ENSOCUP00000008420	ENSOCUP00000007111	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...]	0.620