STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VWFVon Willebrand factor. (2788 aa)    
Predicted Functional Partners:
ITGA2B
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
   
 0.999
F8
Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family.
   
 0.999
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.991
GP9
Glycoprotein IX platelet.
   
 0.984
FN1
Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
   
 0.979
GP1BA
Glycoprotein Ib platelet subunit alpha.
    
 0.975
ADAMTS13
ACR domain-containing protein.
    
 0.965
GP5
Glycoprotein V platelet.
   
 0.957
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.957
F10
Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.
     
 0.952
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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