node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KCNA1 | KCNA6 | ENSOCUP00000015589 | ENSOCUP00000013786 | BTB domain-containing protein; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | 0.461 |
KCNA1 | KCNAB2 | ENSOCUP00000015589 | ENSOCUP00000024124 | BTB domain-containing protein; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | 0.883 |
KCNA1 | KCNB1 | ENSOCUP00000015589 | ENSOCUP00000017212 | BTB domain-containing protein; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms [...] | 0.412 |
KCNA2 | KCNA6 | ENSOCUP00000007687 | ENSOCUP00000013786 | Potassium voltage-gated channel subfamily A member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form funct [...] | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | 0.453 |
KCNA2 | KCNAB2 | ENSOCUP00000007687 | ENSOCUP00000024124 | Potassium voltage-gated channel subfamily A member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form funct [...] | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | 0.909 |
KCNA2 | KCNB1 | ENSOCUP00000007687 | ENSOCUP00000017212 | Potassium voltage-gated channel subfamily A member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form funct [...] | Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms [...] | 0.422 |
KCNA4 | KCNAB2 | ENSOCUP00000049003 | ENSOCUP00000024124 | BTB domain-containing protein; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | 0.899 |
KCNA4 | KCNB1 | ENSOCUP00000049003 | ENSOCUP00000017212 | BTB domain-containing protein; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily B member 1; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Plays also a role in the regulation of exocytosis independently of its electrical function. Forms [...] | 0.415 |
KCNA5 | KCNA6 | ENSOCUP00000017544 | ENSOCUP00000013786 | Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | 0.403 |
KCNA5 | KCNAB2 | ENSOCUP00000017544 | ENSOCUP00000024124 | Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | 0.811 |
KCNA6 | KCNA1 | ENSOCUP00000013786 | ENSOCUP00000015589 | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | BTB domain-containing protein; Belongs to the potassium channel family. | 0.461 |
KCNA6 | KCNA2 | ENSOCUP00000013786 | ENSOCUP00000007687 | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form funct [...] | 0.453 |
KCNA6 | KCNA5 | ENSOCUP00000013786 | ENSOCUP00000017544 | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] | 0.403 |
KCNA6 | KCNAB2 | ENSOCUP00000013786 | ENSOCUP00000024124 | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | 0.767 |
KCNA7 | KCNAB2 | ENSOCUP00000017354 | ENSOCUP00000024124 | Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | 0.778 |
KCNAB2 | KCNA1 | ENSOCUP00000024124 | ENSOCUP00000015589 | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | BTB domain-containing protein; Belongs to the potassium channel family. | 0.883 |
KCNAB2 | KCNA2 | ENSOCUP00000024124 | ENSOCUP00000007687 | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | Potassium voltage-gated channel subfamily A member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and the central nervous system, but also in the cardiovascular system. Prevents aberrant action potential firing and regulates neuronal output. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form funct [...] | 0.909 |
KCNAB2 | KCNA4 | ENSOCUP00000024124 | ENSOCUP00000049003 | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | BTB domain-containing protein; Belongs to the potassium channel family. | 0.899 |
KCNAB2 | KCNA5 | ENSOCUP00000024124 | ENSOCUP00000017544 | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium- selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well [...] | 0.811 |
KCNAB2 | KCNA6 | ENSOCUP00000024124 | ENSOCUP00000013786 | Potassium voltage-gated channel subfamily A regulatory beta subunit 2. | Potassium voltage-gated channel subfamily A member 6; Belongs to the potassium channel family. | 0.767 |