node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BEST1 | MERTK | ENSOCUP00000012113 | ENSOCUP00000024856 | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. | MER proto-oncogene, tyrosine kinase. | 0.698 |
BEST1 | RPE65 | ENSOCUP00000012113 | ENSOCUP00000011739 | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. | Retinoid isomerohydrolase RPE65. | 0.891 |
C1QA | CX3CR1 | ENSOCUP00000026373 | ENSOCUP00000024608 | Complement C1q A chain. | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | 0.708 |
C1QA | LOC100348748 | ENSOCUP00000026373 | ENSOCUP00000041613 | Complement C1q A chain. | IGv domain-containing protein. | 0.862 |
C1QA | MERTK | ENSOCUP00000026373 | ENSOCUP00000024856 | Complement C1q A chain. | MER proto-oncogene, tyrosine kinase. | 0.634 |
C1QA | PROS1 | ENSOCUP00000026373 | ENSOCUP00000018723 | Complement C1q A chain. | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | 0.671 |
CX3CR1 | C1QA | ENSOCUP00000024608 | ENSOCUP00000026373 | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | Complement C1q A chain. | 0.708 |
CX3CR1 | LGALS3 | ENSOCUP00000024608 | ENSOCUP00000044843 | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.411 |
CX3CR1 | LOC100348748 | ENSOCUP00000024608 | ENSOCUP00000041613 | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | IGv domain-containing protein. | 0.831 |
CX3CR1 | MERTK | ENSOCUP00000024608 | ENSOCUP00000024856 | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | MER proto-oncogene, tyrosine kinase. | 0.704 |
LGALS3 | CX3CR1 | ENSOCUP00000044843 | ENSOCUP00000024608 | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | 0.411 |
LGALS3 | LOC100348748 | ENSOCUP00000044843 | ENSOCUP00000041613 | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | IGv domain-containing protein. | 0.663 |
LGALS3 | MERTK | ENSOCUP00000044843 | ENSOCUP00000024856 | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | MER proto-oncogene, tyrosine kinase. | 0.690 |
LOC100348748 | C1QA | ENSOCUP00000041613 | ENSOCUP00000026373 | IGv domain-containing protein. | Complement C1q A chain. | 0.862 |
LOC100348748 | CX3CR1 | ENSOCUP00000041613 | ENSOCUP00000024608 | IGv domain-containing protein. | CX3C chemokine receptor 1; Receptor for the CX3C chemokine fractalkine (CX3CL1); binds to CX3CL1 and mediates both its adhesive and migratory functions. | 0.831 |
LOC100348748 | LGALS3 | ENSOCUP00000041613 | ENSOCUP00000044843 | IGv domain-containing protein. | Galectin-3; Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage [...] | 0.663 |
LOC100348748 | MERTK | ENSOCUP00000041613 | ENSOCUP00000024856 | IGv domain-containing protein. | MER proto-oncogene, tyrosine kinase. | 0.681 |
LOC100348748 | PROS1 | ENSOCUP00000041613 | ENSOCUP00000018723 | IGv domain-containing protein. | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | 0.482 |
MEGF10 | MERTK | ENSOCUP00000003229 | ENSOCUP00000024856 | Multiple EGF like domains 10. | MER proto-oncogene, tyrosine kinase. | 0.772 |
MERTK | BEST1 | ENSOCUP00000024856 | ENSOCUP00000012113 | MER proto-oncogene, tyrosine kinase. | Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family. | 0.698 |