STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLIS3GLIS family zinc finger 3. (770 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.839
SPOPL
Speckle type BTB/POZ protein like.
   
 0.695
SPOP
Speckle type BTB/POZ protein.
   
 0.695
STK36
Serine/threonine kinase 36.
    
 0.685
KIF21B
Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.681
KIF27
Kinesin family member 27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.681
HHEX
Homeobox domain-containing protein.
    
 
 0.591
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
      
 0.571
RFX6
Regulatory factor X6.
    
 
 0.560
ABCC5
ATP binding cassette subfamily C member 5.
    
 
 0.554
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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