OSM protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OSM

Uncharacterized protein. (333 aa)

Predicted Functional Partners:

OSMR

0.999

LIFR

0.998

IL6ST

0.961

JAK2

0.930

LIF

0.921

JAK1

0.921

CTF1

0.912

HGF

0.870

IL6

0.846

CNTF

0.829

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNTF	CTF1	ENSOCUP00000004675	ENSOCUP00000004929	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Cardiotrophin 1.	0.854
CNTF	HGF	ENSOCUP00000004675	ENSOCUP00000030750	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Heptapoietin A light chain; HPTA is an acidic heparin-binding growth factor for hepatocytes.	0.431
CNTF	IL6	ENSOCUP00000004675	ENSOCUP00000017266	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.821
CNTF	IL6ST	ENSOCUP00000004675	ENSOCUP00000006777	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Interleukin 6 signal transducer.	0.949
CNTF	JAK1	ENSOCUP00000004675	ENSOCUP00000005398	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Tyrosine-protein kinase.	0.532
CNTF	JAK2	ENSOCUP00000004675	ENSOCUP00000014491	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Tyrosine-protein kinase.	0.634
CNTF	LIF	ENSOCUP00000004675	ENSOCUP00000003262	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	LIF interleukin 6 family cytokine.	0.915
CNTF	LIFR	ENSOCUP00000004675	ENSOCUP00000002891	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	LIF receptor subunit alpha.	0.997
CNTF	OSM	ENSOCUP00000004675	ENSOCUP00000008790	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Uncharacterized protein.	0.829
CNTF	OSMR	ENSOCUP00000004675	ENSOCUP00000010891	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	Oncostatin M receptor.	0.874
CTF1	CNTF	ENSOCUP00000004929	ENSOCUP00000004675	Cardiotrophin 1.	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	0.854
CTF1	IL6	ENSOCUP00000004929	ENSOCUP00000017266	Cardiotrophin 1.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]	0.686
CTF1	IL6ST	ENSOCUP00000004929	ENSOCUP00000006777	Cardiotrophin 1.	Interleukin 6 signal transducer.	0.448
CTF1	JAK1	ENSOCUP00000004929	ENSOCUP00000005398	Cardiotrophin 1.	Tyrosine-protein kinase.	0.621
CTF1	JAK2	ENSOCUP00000004929	ENSOCUP00000014491	Cardiotrophin 1.	Tyrosine-protein kinase.	0.652
CTF1	LIF	ENSOCUP00000004929	ENSOCUP00000003262	Cardiotrophin 1.	LIF interleukin 6 family cytokine.	0.887
CTF1	LIFR	ENSOCUP00000004929	ENSOCUP00000002891	Cardiotrophin 1.	LIF receptor subunit alpha.	0.944
CTF1	OSM	ENSOCUP00000004929	ENSOCUP00000008790	Cardiotrophin 1.	Uncharacterized protein.	0.912
CTF1	OSMR	ENSOCUP00000004929	ENSOCUP00000010891	Cardiotrophin 1.	Oncostatin M receptor.	0.772
HGF	CNTF	ENSOCUP00000030750	ENSOCUP00000004675	Heptapoietin A light chain; HPTA is an acidic heparin-binding growth factor for hepatocytes.	Ciliary neurotrophic factor; CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.	0.431