SPTBN1 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPTBN1

Spectrin beta chain; Belongs to the spectrin family. (2156 aa)

Predicted Functional Partners:

SPTAN1

0.935

SPTA1

0.887

ANK3

0.810

ANK2

0.774

ANK1

0.742

ITSN2

0.684

ENSOCUP00000041246

0.659

DCTN4

0.659

CAPZB

0.587

EPB41L3

0.552

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANK1	ANK2	ENSOCUP00000015935	ENSOCUP00000035379	Ankyrin 1.	Ankyrin 2.	0.913
ANK1	ANK3	ENSOCUP00000015935	ENSOCUP00000003069	Ankyrin 1.	Ankyrin 3.	0.942
ANK1	ENSOCUP00000041246	ENSOCUP00000015935	ENSOCUP00000041246	Ankyrin 1.	Uncharacterized protein.	0.894
ANK1	SPTA1	ENSOCUP00000015935	ENSOCUP00000006718	Ankyrin 1.	Spectrin alpha, erythrocytic 1.	0.748
ANK1	SPTAN1	ENSOCUP00000015935	ENSOCUP00000010632	Ankyrin 1.	Spectrin alpha, non-erythrocytic 1.	0.720
ANK1	SPTBN1	ENSOCUP00000015935	ENSOCUP00000027291	Ankyrin 1.	Spectrin beta chain; Belongs to the spectrin family.	0.742
ANK2	ANK1	ENSOCUP00000035379	ENSOCUP00000015935	Ankyrin 2.	Ankyrin 1.	0.913
ANK2	ANK3	ENSOCUP00000035379	ENSOCUP00000003069	Ankyrin 2.	Ankyrin 3.	0.912
ANK2	SPTA1	ENSOCUP00000035379	ENSOCUP00000006718	Ankyrin 2.	Spectrin alpha, erythrocytic 1.	0.556
ANK2	SPTAN1	ENSOCUP00000035379	ENSOCUP00000010632	Ankyrin 2.	Spectrin alpha, non-erythrocytic 1.	0.827
ANK2	SPTBN1	ENSOCUP00000035379	ENSOCUP00000027291	Ankyrin 2.	Spectrin beta chain; Belongs to the spectrin family.	0.774
ANK3	ANK1	ENSOCUP00000003069	ENSOCUP00000015935	Ankyrin 3.	Ankyrin 1.	0.942
ANK3	ANK2	ENSOCUP00000003069	ENSOCUP00000035379	Ankyrin 3.	Ankyrin 2.	0.912
ANK3	SPTA1	ENSOCUP00000003069	ENSOCUP00000006718	Ankyrin 3.	Spectrin alpha, erythrocytic 1.	0.600
ANK3	SPTAN1	ENSOCUP00000003069	ENSOCUP00000010632	Ankyrin 3.	Spectrin alpha, non-erythrocytic 1.	0.758
ANK3	SPTBN1	ENSOCUP00000003069	ENSOCUP00000027291	Ankyrin 3.	Spectrin beta chain; Belongs to the spectrin family.	0.810
CAPZB	DCTN4	ENSOCUP00000012649	ENSOCUP00000049261	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Dynactin subunit 4.	0.963
CAPZB	SPTBN1	ENSOCUP00000012649	ENSOCUP00000027291	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Spectrin beta chain; Belongs to the spectrin family.	0.587
DCTN4	CAPZB	ENSOCUP00000049261	ENSOCUP00000012649	Dynactin subunit 4.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.963
DCTN4	SPTBN1	ENSOCUP00000049261	ENSOCUP00000027291	Dynactin subunit 4.	Spectrin beta chain; Belongs to the spectrin family.	0.659