STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAFA4TAFA chemokine like family member 4. (201 aa)    
Predicted Functional Partners:
TMEM25-2
Transmembrane protein 25.
      
 0.629
TMEM25
Ig-like domain-containing protein.
      
 0.629
FPR1
fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity).
      
 0.558
FAM3D
Family with sequence similarity 3 member D.
      
 0.542
PIP5KL1
Phosphatidylinositol-4-phosphate 5-kinase like 1.
      
 0.541
PHACTR3
Phosphatase and actin regulator.
      
 0.532
ANKRD13B
Ankyrin repeat domain 13B.
      
 0.531
EIF4E1B
Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.
      
 0.528
GJC3
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
      
 0.474
PIEZO2
Piezo-type mechanosensitive ion channel component.
      
 0.457
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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