STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM1Isthmin 1. (484 aa)    
Predicted Functional Partners:
SPTLC1
Serine palmitoyltransferase long chain base subunit 1.
 
 
 0.934
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.745
SORD
Sorbitol dehydrogenase.
  
 
 0.724
SPTSSA
Uncharacterized protein.
    
 0.663
SUSD2
Sushi domain containing 2.
      
 0.654
ACKR4
Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
      
 0.610
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.605
ORMDL1
Uncharacterized protein.
    
 
 0.605
ORMDL2
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.605
CALN1
Calneuron 1.
   
  
 0.575
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.