RGS5 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

RGS5

Regulator of G protein signaling 5. (193 aa)

Predicted Functional Partners:

PDGFRB

0.699

GNB5

0.685

GNA12

0.625

RGS4

0.614

GNAT2

0.604

GNAT3

0.604

RGS3

0.599

GNAI2

0.598

GNA14

0.589

GNAQ

0.589

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNA12	GNB5	ENSOCUP00000001272	ENSOCUP00000010220	G protein subunit alpha 12.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.822
GNA12	RGS3	ENSOCUP00000001272	ENSOCUP00000007126	G protein subunit alpha 12.	Regulator of G protein signaling 3.	0.506
GNA12	RGS4	ENSOCUP00000001272	ENSOCUP00000041461	G protein subunit alpha 12.	Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)- alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).	0.561
GNA12	RGS5	ENSOCUP00000001272	ENSOCUP00000028962	G protein subunit alpha 12.	Regulator of G protein signaling 5.	0.625
GNA14	GNAQ	ENSOCUP00000004776	ENSOCUP00000014234	G protein subunit alpha 14.	G protein subunit alpha q.	0.902
GNA14	GNB5	ENSOCUP00000004776	ENSOCUP00000010220	G protein subunit alpha 14.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.923
GNA14	RGS3	ENSOCUP00000004776	ENSOCUP00000007126	G protein subunit alpha 14.	Regulator of G protein signaling 3.	0.638
GNA14	RGS4	ENSOCUP00000004776	ENSOCUP00000041461	G protein subunit alpha 14.	Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)- alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).	0.641
GNA14	RGS5	ENSOCUP00000004776	ENSOCUP00000028962	G protein subunit alpha 14.	Regulator of G protein signaling 5.	0.589
GNAI2	GNAT3	ENSOCUP00000019624	ENSOCUP00000022632	G protein subunit alpha i2.	G protein subunit alpha transducin 3.	0.529
GNAI2	GNB5	ENSOCUP00000019624	ENSOCUP00000010220	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.905
GNAI2	RGS3	ENSOCUP00000019624	ENSOCUP00000007126	G protein subunit alpha i2.	Regulator of G protein signaling 3.	0.955
GNAI2	RGS4	ENSOCUP00000019624	ENSOCUP00000041461	G protein subunit alpha i2.	Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)- alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).	0.789
GNAI2	RGS5	ENSOCUP00000019624	ENSOCUP00000028962	G protein subunit alpha i2.	Regulator of G protein signaling 5.	0.598
GNAQ	GNA14	ENSOCUP00000014234	ENSOCUP00000004776	G protein subunit alpha q.	G protein subunit alpha 14.	0.902
GNAQ	GNB5	ENSOCUP00000014234	ENSOCUP00000010220	G protein subunit alpha q.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.885
GNAQ	RGS3	ENSOCUP00000014234	ENSOCUP00000007126	G protein subunit alpha q.	Regulator of G protein signaling 3.	0.638
GNAQ	RGS4	ENSOCUP00000014234	ENSOCUP00000041461	G protein subunit alpha q.	Regulator of G-protein signaling 4; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)- alpha-1 is inhibited by palmitoylation of the G-protein (By similarity).	0.665
GNAQ	RGS5	ENSOCUP00000014234	ENSOCUP00000028962	G protein subunit alpha q.	Regulator of G protein signaling 5.	0.589
GNAT2	GNAT3	ENSOCUP00000004824	ENSOCUP00000022632	G protein subunit alpha transducin 2.	G protein subunit alpha transducin 3.	0.583