HSPA8 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAG3	DNAJA1	ENSOCUP00000010054	ENSOCUP00000004178	BCL2 associated athanogene 3.	Uncharacterized protein.	0.599
BAG3	DNAJA2	ENSOCUP00000010054	ENSOCUP00000004186	BCL2 associated athanogene 3.	DnaJ heat shock protein family (Hsp40) member A2.	0.487
BAG3	DNAJB4	ENSOCUP00000010054	ENSOCUP00000010909	BCL2 associated athanogene 3.	DnaJ heat shock protein family (Hsp40) member B4.	0.718
BAG3	HSP90AA1	ENSOCUP00000010054	ENSOCUP00000036544	BCL2 associated athanogene 3.	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.419
BAG3	HSP90B1	ENSOCUP00000010054	ENSOCUP00000014008	BCL2 associated athanogene 3.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.	0.534
BAG3	HSPA4	ENSOCUP00000010054	ENSOCUP00000007228	BCL2 associated athanogene 3.	Heat shock protein family A (Hsp70) member 4.	0.974
BAG3	HSPA5	ENSOCUP00000010054	ENSOCUP00000029180	BCL2 associated athanogene 3.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.781
BAG3	HSPA8	ENSOCUP00000010054	ENSOCUP00000029474	BCL2 associated athanogene 3.	Uncharacterized protein.	0.876
DNAJA1	BAG3	ENSOCUP00000004178	ENSOCUP00000010054	Uncharacterized protein.	BCL2 associated athanogene 3.	0.599
DNAJA1	DNAJA2	ENSOCUP00000004178	ENSOCUP00000004186	Uncharacterized protein.	DnaJ heat shock protein family (Hsp40) member A2.	0.777
DNAJA1	DNAJB4	ENSOCUP00000004178	ENSOCUP00000010909	Uncharacterized protein.	DnaJ heat shock protein family (Hsp40) member B4.	0.698
DNAJA1	HSP90AA1	ENSOCUP00000004178	ENSOCUP00000036544	Uncharacterized protein.	Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]	0.784
DNAJA1	HSP90AB1	ENSOCUP00000004178	ENSOCUP00000012976	Uncharacterized protein.	Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...]	0.782
DNAJA1	HSP90B1	ENSOCUP00000004178	ENSOCUP00000014008	Uncharacterized protein.	Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.	0.639
DNAJA1	HSPA4	ENSOCUP00000004178	ENSOCUP00000007228	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 4.	0.690
DNAJA1	HSPA5	ENSOCUP00000004178	ENSOCUP00000029180	Uncharacterized protein.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.865
DNAJA1	HSPA8	ENSOCUP00000004178	ENSOCUP00000029474	Uncharacterized protein.	Uncharacterized protein.	0.922
DNAJA1	HSPD1	ENSOCUP00000004178	ENSOCUP00000010958	Uncharacterized protein.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.409
DNAJA2	BAG3	ENSOCUP00000004186	ENSOCUP00000010054	DnaJ heat shock protein family (Hsp40) member A2.	BCL2 associated athanogene 3.	0.487
DNAJA2	DNAJA1	ENSOCUP00000004186	ENSOCUP00000004178	DnaJ heat shock protein family (Hsp40) member A2.	Uncharacterized protein.	0.777