node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACE | ACE2 | ENSOCUP00000022251 | ENSOCUP00000015275 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Angiotensin-converting enzyme. | 0.523 |
ACE | AGT | ENSOCUP00000022251 | ENSOCUP00000000417 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Angiotensinogen; Belongs to the serpin family. | 0.979 |
ACE | MGRA | ENSOCUP00000022251 | ENSOCUP00000031608 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Mas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. | 0.562 |
ACE | REN | ENSOCUP00000022251 | ENSOCUP00000017597 | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | Renin; Belongs to the peptidase A1 family. | 0.981 |
ACE2 | ACE | ENSOCUP00000015275 | ENSOCUP00000022251 | Angiotensin-converting enzyme. | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | 0.523 |
ACE2 | AGT | ENSOCUP00000015275 | ENSOCUP00000000417 | Angiotensin-converting enzyme. | Angiotensinogen; Belongs to the serpin family. | 0.985 |
ACE2 | LOC103351595 | ENSOCUP00000015275 | ENSOCUP00000037472 | Angiotensin-converting enzyme. | Angiotensin-converting enzyme. | 0.490 |
ACE2 | MGRA | ENSOCUP00000015275 | ENSOCUP00000031608 | Angiotensin-converting enzyme. | Mas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. | 0.634 |
ACE2 | REN | ENSOCUP00000015275 | ENSOCUP00000017597 | Angiotensin-converting enzyme. | Renin; Belongs to the peptidase A1 family. | 0.981 |
AGT | ACE | ENSOCUP00000000417 | ENSOCUP00000022251 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | 0.979 |
AGT | ACE2 | ENSOCUP00000000417 | ENSOCUP00000015275 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme. | 0.985 |
AGT | LOC103351595 | ENSOCUP00000000417 | ENSOCUP00000037472 | Angiotensinogen; Belongs to the serpin family. | Angiotensin-converting enzyme. | 0.979 |
AGT | MGRA | ENSOCUP00000000417 | ENSOCUP00000031608 | Angiotensinogen; Belongs to the serpin family. | Mas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. | 0.952 |
AGT | REN | ENSOCUP00000000417 | ENSOCUP00000017597 | Angiotensinogen; Belongs to the serpin family. | Renin; Belongs to the peptidase A1 family. | 0.945 |
LOC103351595 | ACE2 | ENSOCUP00000037472 | ENSOCUP00000015275 | Angiotensin-converting enzyme. | Angiotensin-converting enzyme. | 0.490 |
LOC103351595 | AGT | ENSOCUP00000037472 | ENSOCUP00000000417 | Angiotensin-converting enzyme. | Angiotensinogen; Belongs to the serpin family. | 0.979 |
LOC103351595 | MGRA | ENSOCUP00000037472 | ENSOCUP00000031608 | Angiotensin-converting enzyme. | Mas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. | 0.532 |
LOC103351595 | REN | ENSOCUP00000037472 | ENSOCUP00000017597 | Angiotensin-converting enzyme. | Renin; Belongs to the peptidase A1 family. | 0.981 |
MGRA | ACE | ENSOCUP00000031608 | ENSOCUP00000022251 | Mas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. | Angiotensin-converting enzyme, soluble form; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI- anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety (By similarity); Belongs to the peptidase M2 family. | 0.562 |
MGRA | ACE2 | ENSOCUP00000031608 | ENSOCUP00000015275 | Mas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. | Angiotensin-converting enzyme. | 0.634 |