node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSOCUP00000036183 | FEN1 | ENSOCUP00000036183 | ENSOCUP00000002851 | Reverse transcriptase domain-containing protein. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.504 |
ENSOCUP00000036183 | LIG1 | ENSOCUP00000036183 | ENSOCUP00000010183 | Reverse transcriptase domain-containing protein. | DNA ligase. | 0.468 |
ENSOCUP00000036183 | MUTYH | ENSOCUP00000036183 | ENSOCUP00000015028 | Reverse transcriptase domain-containing protein. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.477 |
ENSOCUP00000036183 | OGG1 | ENSOCUP00000036183 | ENSOCUP00000013733 | Reverse transcriptase domain-containing protein. | OGG_N domain-containing protein. | 0.461 |
ENSOCUP00000036183 | PCNA | ENSOCUP00000036183 | ENSOCUP00000003512 | Reverse transcriptase domain-containing protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.544 |
ENSOCUP00000036183 | SNRPD3 | ENSOCUP00000036183 | ENSOCUP00000004188 | Reverse transcriptase domain-containing protein. | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. | 0.503 |
ENSOCUP00000036183 | SNRPF | ENSOCUP00000036183 | ENSOCUP00000009401 | Reverse transcriptase domain-containing protein. | Small nuclear ribonucleoprotein polypeptide F. | 0.433 |
FEN1 | ENSOCUP00000036183 | ENSOCUP00000002851 | ENSOCUP00000036183 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Reverse transcriptase domain-containing protein. | 0.504 |
FEN1 | LIG1 | ENSOCUP00000002851 | ENSOCUP00000010183 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.995 |
FEN1 | MUTYH | ENSOCUP00000002851 | ENSOCUP00000015028 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.792 |
FEN1 | OGG1 | ENSOCUP00000002851 | ENSOCUP00000013733 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | OGG_N domain-containing protein. | 0.923 |
FEN1 | PCNA | ENSOCUP00000002851 | ENSOCUP00000003512 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.999 |
LIG1 | ENSOCUP00000036183 | ENSOCUP00000010183 | ENSOCUP00000036183 | DNA ligase. | Reverse transcriptase domain-containing protein. | 0.468 |
LIG1 | FEN1 | ENSOCUP00000010183 | ENSOCUP00000002851 | DNA ligase. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.995 |
LIG1 | MUTYH | ENSOCUP00000010183 | ENSOCUP00000015028 | DNA ligase. | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.529 |
LIG1 | OGG1 | ENSOCUP00000010183 | ENSOCUP00000013733 | DNA ligase. | OGG_N domain-containing protein. | 0.800 |
LIG1 | PCNA | ENSOCUP00000010183 | ENSOCUP00000003512 | DNA ligase. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.998 |
MUTYH | ENSOCUP00000036183 | ENSOCUP00000015028 | ENSOCUP00000036183 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Reverse transcriptase domain-containing protein. | 0.477 |
MUTYH | FEN1 | ENSOCUP00000015028 | ENSOCUP00000002851 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.792 |
MUTYH | LIG1 | ENSOCUP00000015028 | ENSOCUP00000010183 | Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. | DNA ligase. | 0.529 |