node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APOA1 | APOA5 | ENSOCUP00000009241 | ENSOCUP00000041415 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Uncharacterized protein. | 0.813 |
APOA1 | CETP | ENSOCUP00000009241 | ENSOCUP00000011306 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | 0.967 |
APOA1 | LIPG | ENSOCUP00000009241 | ENSOCUP00000036553 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | PLAT domain-containing protein. | 0.565 |
APOA5 | APOA1 | ENSOCUP00000041415 | ENSOCUP00000009241 | Uncharacterized protein. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.813 |
APOA5 | CETP | ENSOCUP00000041415 | ENSOCUP00000011306 | Uncharacterized protein. | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | 0.762 |
APOA5 | LIPG | ENSOCUP00000041415 | ENSOCUP00000036553 | Uncharacterized protein. | PLAT domain-containing protein. | 0.578 |
BSND | LIPG | ENSOCUP00000003918 | ENSOCUP00000036553 | Uncharacterized protein. | PLAT domain-containing protein. | 0.513 |
BSND | PCSK1 | ENSOCUP00000003918 | ENSOCUP00000010457 | Uncharacterized protein. | Proprotein convertase subtilisin/kexin type 1. | 0.639 |
BSND | PCSK7 | ENSOCUP00000003918 | ENSOCUP00000010298 | Uncharacterized protein. | Proprotein convertase subtilisin/kexin type 7. | 0.627 |
BSND | USP24 | ENSOCUP00000003918 | ENSOCUP00000013429 | Uncharacterized protein. | Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. | 0.631 |
CETP | APOA1 | ENSOCUP00000011306 | ENSOCUP00000009241 | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.967 |
CETP | APOA5 | ENSOCUP00000011306 | ENSOCUP00000041415 | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | Uncharacterized protein. | 0.762 |
CETP | LIPG | ENSOCUP00000011306 | ENSOCUP00000036553 | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | PLAT domain-containing protein. | 0.620 |
LIPG | APOA1 | ENSOCUP00000036553 | ENSOCUP00000009241 | PLAT domain-containing protein. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.565 |
LIPG | APOA5 | ENSOCUP00000036553 | ENSOCUP00000041415 | PLAT domain-containing protein. | Uncharacterized protein. | 0.578 |
LIPG | BSND | ENSOCUP00000036553 | ENSOCUP00000003918 | PLAT domain-containing protein. | Uncharacterized protein. | 0.513 |
LIPG | CETP | ENSOCUP00000036553 | ENSOCUP00000011306 | PLAT domain-containing protein. | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (By similarity). | 0.620 |
LIPG | LIPM | ENSOCUP00000036553 | ENSOCUP00000021440 | PLAT domain-containing protein. | Lipase; Belongs to the AB hydrolase superfamily. Lipase family. | 0.513 |
LIPG | PCSK1 | ENSOCUP00000036553 | ENSOCUP00000010457 | PLAT domain-containing protein. | Proprotein convertase subtilisin/kexin type 1. | 0.644 |
LIPG | PCSK7 | ENSOCUP00000036553 | ENSOCUP00000010298 | PLAT domain-containing protein. | Proprotein convertase subtilisin/kexin type 7. | 0.589 |