node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AHCY | AHCYL1 | ENSOCUP00000007427 | ENSOCUP00000008381 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | 0.925 |
AHCY | BHMT | ENSOCUP00000007427 | ENSOCUP00000031900 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Hcy-binding domain-containing protein. | 0.986 |
AHCY | CBS | ENSOCUP00000007427 | ENSOCUP00000034549 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). | 0.984 |
AHCY | KYAT3 | ENSOCUP00000007427 | ENSOCUP00000030636 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Kynurenine aminotransferase 3. | 0.918 |
AHCY | MTR | ENSOCUP00000007427 | ENSOCUP00000008420 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.984 |
AHCY | SELENBP1 | ENSOCUP00000007427 | ENSOCUP00000040001 | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | Selenium binding protein 1. | 0.808 |
AHCYL1 | AHCY | ENSOCUP00000008381 | ENSOCUP00000007427 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.925 |
AHCYL1 | BHMT | ENSOCUP00000008381 | ENSOCUP00000031900 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Hcy-binding domain-containing protein. | 0.980 |
AHCYL1 | CBS | ENSOCUP00000008381 | ENSOCUP00000034549 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). | 0.980 |
AHCYL1 | KYAT3 | ENSOCUP00000008381 | ENSOCUP00000030636 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Kynurenine aminotransferase 3. | 0.916 |
AHCYL1 | MTR | ENSOCUP00000008381 | ENSOCUP00000008420 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
AHCYL1 | SELENBP1 | ENSOCUP00000008381 | ENSOCUP00000040001 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Selenium binding protein 1. | 0.809 |
BHMT | AHCY | ENSOCUP00000031900 | ENSOCUP00000007427 | Hcy-binding domain-containing protein. | Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family. | 0.986 |
BHMT | AHCYL1 | ENSOCUP00000031900 | ENSOCUP00000008381 | Hcy-binding domain-containing protein. | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | 0.980 |
BHMT | CBS | ENSOCUP00000031900 | ENSOCUP00000034549 | Hcy-binding domain-containing protein. | Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). | 0.982 |
BHMT | KYAT3 | ENSOCUP00000031900 | ENSOCUP00000030636 | Hcy-binding domain-containing protein. | Kynurenine aminotransferase 3. | 0.930 |
BHMT | MPST | ENSOCUP00000031900 | ENSOCUP00000042910 | Hcy-binding domain-containing protein. | Uncharacterized protein. | 0.468 |
BHMT | MTR | ENSOCUP00000031900 | ENSOCUP00000008420 | Hcy-binding domain-containing protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
BHMT | SELENBP1 | ENSOCUP00000031900 | ENSOCUP00000040001 | Hcy-binding domain-containing protein. | Selenium binding protein 1. | 0.819 |
BHMT | TST | ENSOCUP00000031900 | ENSOCUP00000037459 | Hcy-binding domain-containing protein. | Thiosulfate sulfurtransferase. | 0.510 |