| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHCYL1 | AHCYL2 | ENSOCUP00000008381 | ENSOCUP00000030657 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Adenosylhomocysteinase like 2. | 0.998 |
| AHCYL1 | BHMT | ENSOCUP00000008381 | ENSOCUP00000031900 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Hcy-binding domain-containing protein. | 0.951 |
| AHCYL1 | CBS | ENSOCUP00000008381 | ENSOCUP00000034549 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). | 0.933 |
| AHCYL1 | ENSOCUP00000031921 | ENSOCUP00000008381 | ENSOCUP00000031921 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Aminotran_1_2 domain-containing protein. | 0.866 |
| AHCYL1 | KYAT3 | ENSOCUP00000008381 | ENSOCUP00000030636 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Kynurenine aminotransferase 3. | 0.866 |
| AHCYL1 | MTR | ENSOCUP00000008381 | ENSOCUP00000008420 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.943 |
| AHCYL1 | SELENBP1 | ENSOCUP00000008381 | ENSOCUP00000040001 | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | Selenium binding protein 1. | 0.858 |
| AHCYL2 | AHCYL1 | ENSOCUP00000030657 | ENSOCUP00000008381 | Adenosylhomocysteinase like 2. | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | 0.998 |
| AHCYL2 | BHMT | ENSOCUP00000030657 | ENSOCUP00000031900 | Adenosylhomocysteinase like 2. | Hcy-binding domain-containing protein. | 0.951 |
| AHCYL2 | CBS | ENSOCUP00000030657 | ENSOCUP00000034549 | Adenosylhomocysteinase like 2. | Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). | 0.915 |
| AHCYL2 | ENSOCUP00000031921 | ENSOCUP00000030657 | ENSOCUP00000031921 | Adenosylhomocysteinase like 2. | Aminotran_1_2 domain-containing protein. | 0.866 |
| AHCYL2 | KYAT3 | ENSOCUP00000030657 | ENSOCUP00000030636 | Adenosylhomocysteinase like 2. | Kynurenine aminotransferase 3. | 0.866 |
| AHCYL2 | MTR | ENSOCUP00000030657 | ENSOCUP00000008420 | Adenosylhomocysteinase like 2. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.942 |
| AHCYL2 | SELENBP1 | ENSOCUP00000030657 | ENSOCUP00000040001 | Adenosylhomocysteinase like 2. | Selenium binding protein 1. | 0.858 |
| BHMT | AHCYL1 | ENSOCUP00000031900 | ENSOCUP00000008381 | Hcy-binding domain-containing protein. | Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. | 0.951 |
| BHMT | AHCYL2 | ENSOCUP00000031900 | ENSOCUP00000030657 | Hcy-binding domain-containing protein. | Adenosylhomocysteinase like 2. | 0.951 |
| BHMT | CBS | ENSOCUP00000031900 | ENSOCUP00000034549 | Hcy-binding domain-containing protein. | Cystathionine beta-synthase; Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L- homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine (By similarity). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons (By similarity). | 0.958 |
| BHMT | ENSOCUP00000031921 | ENSOCUP00000031900 | ENSOCUP00000031921 | Hcy-binding domain-containing protein. | Aminotran_1_2 domain-containing protein. | 0.869 |
| BHMT | KYAT3 | ENSOCUP00000031900 | ENSOCUP00000030636 | Hcy-binding domain-containing protein. | Kynurenine aminotransferase 3. | 0.869 |
| BHMT | MTR | ENSOCUP00000031900 | ENSOCUP00000008420 | Hcy-binding domain-containing protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.971 |
