node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTB | CD44 | ENSOCUP00000045964 | ENSOCUP00000048202 | Uncharacterized protein. | CD44 molecule (Indian blood group). | 0.524 |
ACTB | EZR | ENSOCUP00000045964 | ENSOCUP00000040029 | Uncharacterized protein. | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | 0.950 |
ACTB | ICAM1 | ENSOCUP00000045964 | ENSOCUP00000027126 | Uncharacterized protein. | Intercellular adhesion molecule 1. | 0.553 |
ACTB | MSN | ENSOCUP00000045964 | ENSOCUP00000000131 | Uncharacterized protein. | FERM domain-containing protein. | 0.927 |
ACTB | RDX | ENSOCUP00000045964 | ENSOCUP00000037499 | Uncharacterized protein. | Radixin. | 0.919 |
CD44 | ACTB | ENSOCUP00000048202 | ENSOCUP00000045964 | CD44 molecule (Indian blood group). | Uncharacterized protein. | 0.524 |
CD44 | EZR | ENSOCUP00000048202 | ENSOCUP00000040029 | CD44 molecule (Indian blood group). | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | 0.996 |
CD44 | ICAM1 | ENSOCUP00000048202 | ENSOCUP00000027126 | CD44 molecule (Indian blood group). | Intercellular adhesion molecule 1. | 0.990 |
CD44 | ICAM2 | ENSOCUP00000048202 | ENSOCUP00000011071 | CD44 molecule (Indian blood group). | Intercellular adhesion molecule 2. | 0.752 |
CD44 | MSN | ENSOCUP00000048202 | ENSOCUP00000000131 | CD44 molecule (Indian blood group). | FERM domain-containing protein. | 0.988 |
CD44 | RDX | ENSOCUP00000048202 | ENSOCUP00000037499 | CD44 molecule (Indian blood group). | Radixin. | 0.993 |
CD44 | SLC9A1 | ENSOCUP00000048202 | ENSOCUP00000022999 | CD44 molecule (Indian blood group). | Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. | 0.762 |
CD44 | SLC9A3R1 | ENSOCUP00000048202 | ENSOCUP00000001351 | CD44 molecule (Indian blood group). | Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. Involved in sperm capacitation. May participate in the regulation of the chloride and bicarbonate homeostasis in spermatoz [...] | 0.467 |
EZR | ACTB | ENSOCUP00000040029 | ENSOCUP00000045964 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Uncharacterized protein. | 0.950 |
EZR | CD44 | ENSOCUP00000040029 | ENSOCUP00000048202 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | CD44 molecule (Indian blood group). | 0.996 |
EZR | ICAM1 | ENSOCUP00000040029 | ENSOCUP00000027126 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Intercellular adhesion molecule 1. | 0.994 |
EZR | ICAM2 | ENSOCUP00000040029 | ENSOCUP00000011071 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Intercellular adhesion molecule 2. | 0.921 |
EZR | MSN | ENSOCUP00000040029 | ENSOCUP00000000131 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | FERM domain-containing protein. | 0.999 |
EZR | PRKACB | ENSOCUP00000040029 | ENSOCUP00000043583 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.979 |
EZR | PRKCE | ENSOCUP00000040029 | ENSOCUP00000011861 | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] | 0.930 |