STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIEZO2Piezo-type mechanosensitive ion channel component. (2725 aa)    
Predicted Functional Partners:
TIPIN
TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 
 0.942
TIMELESS
Timeless circadian regulator.
    
 
 0.936
CHEK2
Checkpoint kinase 2.
    
 
 0.925
MCM4
DNA helicase; Belongs to the MCM family.
   
 0.924
WDHD1
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.901
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 
 0.895
TP53BP1
Tumor protein p53 binding protein 1.
    
 
 0.884
MCM9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
 0.826
MCM2
DNA helicase; Belongs to the MCM family.
   
 0.826
TRPA1
Transient receptor potential cation channel subfamily A member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.821
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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