PTPN6 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD72	PECAM1	ENSOCUP00000028606	ENSOCUP00000013077	C-type lectin domain-containing protein.	Platelet and endothelial cell adhesion molecule 1.	0.576
CD72	PTPN6	ENSOCUP00000028606	ENSOCUP00000040801	C-type lectin domain-containing protein.	Protein tyrosine phosphatase non-receptor type 6.	0.911
CD72	SYK	ENSOCUP00000028606	ENSOCUP00000015068	C-type lectin domain-containing protein.	Tyrosine-protein kinase.	0.529
CTLA4	GRB2	ENSOCUP00000017677	ENSOCUP00000042433	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	Growth factor receptor bound protein 2.	0.973
CTLA4	LCP2	ENSOCUP00000017677	ENSOCUP00000000465	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	Lymphocyte cytosolic protein 2.	0.406
CTLA4	PTPN6	ENSOCUP00000017677	ENSOCUP00000040801	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	Protein tyrosine phosphatase non-receptor type 6.	0.893
CTLA4	ZAP70	ENSOCUP00000017677	ENSOCUP00000005043	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	Tyrosine-protein kinase.	0.718
GAB1	GAB2	ENSOCUP00000002840	ENSOCUP00000015611	GRB2 associated binding protein 1.	GRB2 associated binding protein 2.	0.856
GAB1	GRB2	ENSOCUP00000002840	ENSOCUP00000042433	GRB2 associated binding protein 1.	Growth factor receptor bound protein 2.	0.998
GAB1	PDGFRB	ENSOCUP00000002840	ENSOCUP00000001483	GRB2 associated binding protein 1.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.863
GAB1	PTPN6	ENSOCUP00000002840	ENSOCUP00000040801	GRB2 associated binding protein 1.	Protein tyrosine phosphatase non-receptor type 6.	0.943
GAB2	GAB1	ENSOCUP00000015611	ENSOCUP00000002840	GRB2 associated binding protein 2.	GRB2 associated binding protein 1.	0.856
GAB2	GRB2	ENSOCUP00000015611	ENSOCUP00000042433	GRB2 associated binding protein 2.	Growth factor receptor bound protein 2.	0.993
GAB2	PDGFRB	ENSOCUP00000015611	ENSOCUP00000001483	GRB2 associated binding protein 2.	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.	0.852
GAB2	PTPN6	ENSOCUP00000015611	ENSOCUP00000040801	GRB2 associated binding protein 2.	Protein tyrosine phosphatase non-receptor type 6.	0.910
GAB2	SYK	ENSOCUP00000015611	ENSOCUP00000015068	GRB2 associated binding protein 2.	Tyrosine-protein kinase.	0.910
GAB2	ZAP70	ENSOCUP00000015611	ENSOCUP00000005043	GRB2 associated binding protein 2.	Tyrosine-protein kinase.	0.772
GRB2	CTLA4	ENSOCUP00000042433	ENSOCUP00000017677	Growth factor receptor bound protein 2.	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	0.973
GRB2	GAB1	ENSOCUP00000042433	ENSOCUP00000002840	Growth factor receptor bound protein 2.	GRB2 associated binding protein 1.	0.998
GRB2	GAB2	ENSOCUP00000042433	ENSOCUP00000015611	Growth factor receptor bound protein 2.	GRB2 associated binding protein 2.	0.993