STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3KBP1SH3 domain containing kinase binding protein 1. (717 aa)    
Predicted Functional Partners:
CBL
Cbl proto-oncogene.
   
 0.990
CBLB
Cbl proto-oncogene B.
   
 0.878
EGFR
Receptor protein-tyrosine kinase.
    
 0.860
G1SK22_RABIT
Ubiquitin-like domain-containing protein.
    
 0.851
G1TZL0_RABIT
Ubiquitin-like domain-containing protein.
    
 0.851
UBB
Ubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11- [...]
    
  0.806
ENSOCUP00000030467
Uncharacterized protein.
    
  0.806
GRB2
Growth factor receptor bound protein 2.
    
0.804
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
   
0.790
DAB1
DAB adaptor protein 1.
    
 0.786
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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