node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTRL | ENSOCUP00000043913 | ENSOCUP00000040851 | ENSOCUP00000043913 | Chymotrypsin like; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein. | 0.576 |
CTRL | KLK6 | ENSOCUP00000040851 | ENSOCUP00000044062 | Chymotrypsin like; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein. | 0.790 |
CTRL | LOC100346323 | ENSOCUP00000040851 | ENSOCUP00000015500 | Chymotrypsin like; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.470 |
CTRL | MET | ENSOCUP00000040851 | ENSOCUP00000003111 | Chymotrypsin like; Belongs to the peptidase S1 family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.537 |
CTRL | MST1R | ENSOCUP00000040851 | ENSOCUP00000008078 | Chymotrypsin like; Belongs to the peptidase S1 family. | Macrophage stimulating 1 receptor. | 0.539 |
ENSOCUP00000033256 | ENSOCUP00000043913 | ENSOCUP00000033256 | ENSOCUP00000043913 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein. | 0.469 |
ENSOCUP00000033256 | KLK6 | ENSOCUP00000033256 | ENSOCUP00000044062 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein. | 0.585 |
ENSOCUP00000033256 | LOC100346323 | ENSOCUP00000033256 | ENSOCUP00000015500 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.470 |
ENSOCUP00000033256 | MET | ENSOCUP00000033256 | ENSOCUP00000003111 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.537 |
ENSOCUP00000033256 | MST1R | ENSOCUP00000033256 | ENSOCUP00000008078 | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | Macrophage stimulating 1 receptor. | 0.539 |
ENSOCUP00000043913 | CTRL | ENSOCUP00000043913 | ENSOCUP00000040851 | Peptidase S1 domain-containing protein. | Chymotrypsin like; Belongs to the peptidase S1 family. | 0.576 |
ENSOCUP00000043913 | ENSOCUP00000033256 | ENSOCUP00000043913 | ENSOCUP00000033256 | Peptidase S1 domain-containing protein. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.469 |
ENSOCUP00000043913 | F10 | ENSOCUP00000043913 | ENSOCUP00000025032 | Peptidase S1 domain-containing protein. | Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family. | 0.487 |
ENSOCUP00000043913 | F12 | ENSOCUP00000043913 | ENSOCUP00000002422 | Peptidase S1 domain-containing protein. | Coagulation factor XII. | 0.478 |
ENSOCUP00000043913 | F7 | ENSOCUP00000043913 | ENSOCUP00000042756 | Peptidase S1 domain-containing protein. | Coagulation factor VII; Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity). | 0.529 |
ENSOCUP00000043913 | KLK6 | ENSOCUP00000043913 | ENSOCUP00000044062 | Peptidase S1 domain-containing protein. | Peptidase S1 domain-containing protein. | 0.478 |
ENSOCUP00000043913 | LOC100346323 | ENSOCUP00000043913 | ENSOCUP00000015500 | Peptidase S1 domain-containing protein. | Uncharacterized protein. | 0.470 |
ENSOCUP00000043913 | MET | ENSOCUP00000043913 | ENSOCUP00000003111 | Peptidase S1 domain-containing protein. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.537 |
ENSOCUP00000043913 | MST1R | ENSOCUP00000043913 | ENSOCUP00000008078 | Peptidase S1 domain-containing protein. | Macrophage stimulating 1 receptor. | 0.539 |
ENSOCUP00000043913 | PROC | ENSOCUP00000043913 | ENSOCUP00000041616 | Peptidase S1 domain-containing protein. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.494 |