node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD69 | TMPRSS13 | ENSOCUP00000007818 | ENSOCUP00000044409 | CD69 molecule. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.525 |
DEPDC4 | TMPRSS13 | ENSOCUP00000020839 | ENSOCUP00000044409 | DEP domain containing 4. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.695 |
FURIN | PRSS8 | ENSOCUP00000029858 | ENSOCUP00000001987 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Serine protease 8; Belongs to the peptidase S1 family. | 0.549 |
FURIN | TMPRSS13 | ENSOCUP00000029858 | ENSOCUP00000044409 | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.632 |
MET | MST1R | ENSOCUP00000003111 | ENSOCUP00000008078 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Macrophage stimulating 1 receptor. | 0.715 |
MET | PRSS8 | ENSOCUP00000003111 | ENSOCUP00000001987 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Serine protease 8; Belongs to the peptidase S1 family. | 0.537 |
MET | TMPRSS13 | ENSOCUP00000003111 | ENSOCUP00000044409 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.537 |
MST1R | MET | ENSOCUP00000008078 | ENSOCUP00000003111 | Macrophage stimulating 1 receptor. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.715 |
MST1R | PRSS8 | ENSOCUP00000008078 | ENSOCUP00000001987 | Macrophage stimulating 1 receptor. | Serine protease 8; Belongs to the peptidase S1 family. | 0.539 |
MST1R | TMPRSS13 | ENSOCUP00000008078 | ENSOCUP00000044409 | Macrophage stimulating 1 receptor. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.539 |
PCSK6 | TMPRSS13 | ENSOCUP00000018331 | ENSOCUP00000044409 | Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.567 |
PCSK7 | TMPRSS13 | ENSOCUP00000010298 | ENSOCUP00000044409 | Proprotein convertase subtilisin/kexin type 7. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.531 |
PRSS8 | FURIN | ENSOCUP00000001987 | ENSOCUP00000029858 | Serine protease 8; Belongs to the peptidase S1 family. | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. | 0.549 |
PRSS8 | MET | ENSOCUP00000001987 | ENSOCUP00000003111 | Serine protease 8; Belongs to the peptidase S1 family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.537 |
PRSS8 | MST1R | ENSOCUP00000001987 | ENSOCUP00000008078 | Serine protease 8; Belongs to the peptidase S1 family. | Macrophage stimulating 1 receptor. | 0.539 |
PRSS8 | SPINT1 | ENSOCUP00000001987 | ENSOCUP00000013205 | Serine protease 8; Belongs to the peptidase S1 family. | Serine peptidase inhibitor, Kunitz type 1. | 0.653 |
PRSS8 | SPINT2 | ENSOCUP00000001987 | ENSOCUP00000042547 | Serine protease 8; Belongs to the peptidase S1 family. | Serine peptidase inhibitor, Kunitz type 2. | 0.675 |
PRSS8 | TMPRSS13 | ENSOCUP00000001987 | ENSOCUP00000044409 | Serine protease 8; Belongs to the peptidase S1 family. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.533 |
SPINT1 | PRSS8 | ENSOCUP00000013205 | ENSOCUP00000001987 | Serine peptidase inhibitor, Kunitz type 1. | Serine protease 8; Belongs to the peptidase S1 family. | 0.653 |
SPINT1 | TMPRSS13 | ENSOCUP00000013205 | ENSOCUP00000044409 | Serine peptidase inhibitor, Kunitz type 1. | Transmembrane serine protease 13; Belongs to the peptidase S1 family. | 0.537 |