STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADM2Adrenomedullin 2. (178 aa)    
Predicted Functional Partners:
CALCRL
Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.976
RAMP2
Receptor activity modifying protein 2.
     
 0.852
ADM
Adrenomedullin.
     
 0.836
CALCR
Calcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Isoform 2 has altered ligand binding and abolished coupling to phospholipase C.
    
 0.826
IAPP
Islet amyloid polypeptide; Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism; Belongs to the calcitonin family.
     
 0.652
G1TCA5_RABIT
Uncharacterized protein.
     
 0.570
HDGFL3
HDGF like 3.
      
 0.550
ENSOCUP00000034349
Uncharacterized protein.
    
 0.524
GNAS
GNAS complex locus.
    
 0.524
KLHDC7B
Uncharacterized protein.
      
 0.495
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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