STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MOV10Mov10 RISC complex RNA helicase. (1013 aa)    
Predicted Functional Partners:
AGO1
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
    
 0.903
AGO2
Protein argonaute-2; Belongs to the argonaute family.
    
 0.882
DICER1
Uncharacterized protein.
      
 0.732
DHX9
DExH-box helicase 9.
    
 0.718
RNASEL
Uncharacterized protein.
   
 0.696
DDX6
DEAD-box helicase 6; Belongs to the DEAD box helicase family.
    
 0.630
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
   
  
 0.627
DDX10
RNA helicase.
    
 0.607
DDX1
DEAD-box helicase 1.
    
 0.576
TRIM28
Tripartite motif containing 28.
   
 
 0.573
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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