HDAC6 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

HDAC6

Histone deacetylase 6. (1257 aa)

Predicted Functional Partners:

VCP

0.974

CTTN

0.948

SQSTM1

0.947

SIRT2

0.943

TARDBP

0.913

EP300

0.897

CFTR

0.895

H2BC18

0.889

MACROH2A2

0.884

MACROH2A1

0.884

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	HDAC6	ENSOCUP00000034709	ENSOCUP00000048938	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Histone deacetylase 6.	0.895
CFTR	SQSTM1	ENSOCUP00000034709	ENSOCUP00000013263	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sequestosome 1.	0.607
CFTR	TARDBP	ENSOCUP00000034709	ENSOCUP00000003504	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	TAR DNA binding protein.	0.401
CFTR	VCP	ENSOCUP00000034709	ENSOCUP00000005566	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Valosin containing protein; Belongs to the AAA ATPase family.	0.946
CTTN	HDAC6	ENSOCUP00000031724	ENSOCUP00000048938	Cortactin.	Histone deacetylase 6.	0.948
EP300	H2BC18	ENSOCUP00000009840	ENSOCUP00000017048	E1A binding protein p300.	Histone H2B; Belongs to the histone H2B family.	0.454
EP300	HDAC6	ENSOCUP00000009840	ENSOCUP00000048938	E1A binding protein p300.	Histone deacetylase 6.	0.897
EP300	SIRT2	ENSOCUP00000009840	ENSOCUP00000039867	E1A binding protein p300.	Sirtuin 2.	0.858
H2BC18	EP300	ENSOCUP00000017048	ENSOCUP00000009840	Histone H2B; Belongs to the histone H2B family.	E1A binding protein p300.	0.454
H2BC18	HDAC6	ENSOCUP00000017048	ENSOCUP00000048938	Histone H2B; Belongs to the histone H2B family.	Histone deacetylase 6.	0.889
H2BC18	MACROH2A1	ENSOCUP00000017048	ENSOCUP00000027405	Histone H2B; Belongs to the histone H2B family.	H2A histone family member Y; Belongs to the histone H2A family.	0.659
H2BC18	MACROH2A2	ENSOCUP00000017048	ENSOCUP00000004128	Histone H2B; Belongs to the histone H2B family.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.607
HDAC6	CFTR	ENSOCUP00000048938	ENSOCUP00000034709	Histone deacetylase 6.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.895
HDAC6	CTTN	ENSOCUP00000048938	ENSOCUP00000031724	Histone deacetylase 6.	Cortactin.	0.948
HDAC6	EP300	ENSOCUP00000048938	ENSOCUP00000009840	Histone deacetylase 6.	E1A binding protein p300.	0.897
HDAC6	H2BC18	ENSOCUP00000048938	ENSOCUP00000017048	Histone deacetylase 6.	Histone H2B; Belongs to the histone H2B family.	0.889
HDAC6	MACROH2A1	ENSOCUP00000048938	ENSOCUP00000027405	Histone deacetylase 6.	H2A histone family member Y; Belongs to the histone H2A family.	0.884
HDAC6	MACROH2A2	ENSOCUP00000048938	ENSOCUP00000004128	Histone deacetylase 6.	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.	0.884
HDAC6	SIRT2	ENSOCUP00000048938	ENSOCUP00000039867	Histone deacetylase 6.	Sirtuin 2.	0.943
HDAC6	SQSTM1	ENSOCUP00000048938	ENSOCUP00000013263	Histone deacetylase 6.	Sequestosome 1.	0.947