STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMIETransmembrane inner ear. (170 aa)    
Predicted Functional Partners:
TMC1
Transmembrane channel-like protein.
   
 
 0.919
LHFPL5
LHFPL tetraspan subfamily member 5.
   
 
 0.813
GJB2
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
   
  
 0.724
USH1C
USH1 protein network component harmonin.
   
  
 0.704
CIB2
Calcium and integrin binding family member 2.
   
 
 0.666
CDH23
Cadherin related 23.
      
 0.648
SLC26A4
Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
   
  
 0.603
TRIOBP
PH domain-containing protein.
   
  
 0.517
LHFPL4
LHFPL tetraspan subfamily member 4.
     
 0.500
ENSOCUP00000036859
Uncharacterized protein.
     
 0.500
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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