PIK3R6 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PIK3R6

Phosphoinositide-3-kinase regulatory subunit 6. (777 aa)

Predicted Functional Partners:

PIK3CG

0.990

PIK3CD

0.962

PIK3CB

0.961

PIK3CA

0.960

PDPK1

0.933

LYN

0.933

PIK3R1

0.932

PIK3R5

0.929

LOC100345250

0.928

FGR

0.927

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FGR	LOC100345250	ENSOCUP00000007706	ENSOCUP00000012307	Tyrosine-protein kinase.	Uncharacterized protein.	0.942
FGR	LYN	ENSOCUP00000007706	ENSOCUP00000002661	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.972
FGR	PDPK1	ENSOCUP00000007706	ENSOCUP00000001849	Tyrosine-protein kinase.	3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily.	0.435
FGR	PIK3CA	ENSOCUP00000007706	ENSOCUP00000026298	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.943
FGR	PIK3CB	ENSOCUP00000007706	ENSOCUP00000004241	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.941
FGR	PIK3CD	ENSOCUP00000007706	ENSOCUP00000021004	Tyrosine-protein kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.944
FGR	PIK3CG	ENSOCUP00000007706	ENSOCUP00000010960	Tyrosine-protein kinase.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.936
FGR	PIK3R1	ENSOCUP00000007706	ENSOCUP00000004433	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.948
FGR	PIK3R5	ENSOCUP00000007706	ENSOCUP00000022513	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 5.	0.941
FGR	PIK3R6	ENSOCUP00000007706	ENSOCUP00000049034	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 6.	0.927
LOC100345250	FGR	ENSOCUP00000012307	ENSOCUP00000007706	Uncharacterized protein.	Tyrosine-protein kinase.	0.942
LOC100345250	LYN	ENSOCUP00000012307	ENSOCUP00000002661	Uncharacterized protein.	Tyrosine-protein kinase.	0.957
LOC100345250	PDPK1	ENSOCUP00000012307	ENSOCUP00000001849	Uncharacterized protein.	3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily.	0.965
LOC100345250	PIK3CA	ENSOCUP00000012307	ENSOCUP00000026298	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.998
LOC100345250	PIK3CB	ENSOCUP00000012307	ENSOCUP00000004241	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.998
LOC100345250	PIK3CD	ENSOCUP00000012307	ENSOCUP00000021004	Uncharacterized protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.995
LOC100345250	PIK3CG	ENSOCUP00000012307	ENSOCUP00000010960	Uncharacterized protein.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.996
LOC100345250	PIK3R1	ENSOCUP00000012307	ENSOCUP00000004433	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 1.	0.994
LOC100345250	PIK3R5	ENSOCUP00000012307	ENSOCUP00000022513	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 5.	0.973
LOC100345250	PIK3R6	ENSOCUP00000012307	ENSOCUP00000049034	Uncharacterized protein.	Phosphoinositide-3-kinase regulatory subunit 6.	0.928