STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM11ADAM metallopeptidase domain 11. (816 aa)    
Predicted Functional Partners:
LGI2
Leucine rich repeat LGI family member 2.
     
 0.781
LGI4
Leucine rich repeat LGI family member 4.
     
 0.725
LGI3
Leucine rich repeat LGI family member 3.
   
 
 0.690
LGI1
Leucine rich glioma inactivated 1.
     
 0.578
PCDHGB5
Protocadherin gamma subfamily B, 5.
     
 0.550
ADAM23
ADAM metallopeptidase domain 23.
  
 
0.536
CADM3
Cell adhesion molecule 3.
      
 0.524
ADAMTSL4
ADAMTS like 4.
    
 
 0.497
CACNG4
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 
 0.496
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.492
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.