Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3BYH8_TETNGTumor necrosis factor receptor superfamily, member a. (428 aa)    
Predicted Functional Partners:
H3DGB3_TETNG
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.972
H3BZ00_TETNG
Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.937
H3CR38_TETNG
Uncharacterized protein; Belongs to the peptidase C14A family.
    
 0.937
H3C779_TETNG
Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family.
    
 0.860
H3CAT0_TETNG
UDP-glucose ceramide glucosyltransferase.
    
   0.825
H3CE94_TETNG
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.814
H3C6S5_TETNG
Tnfrsf1a-associated via death domain.
  
 
 0.789
H3CU64_TETNG
Nedd4 family interacting protein 1.
    
   0.763
Q4RIS3_TETNG
Chromosome 7 SCAF15042, whole genome shotgun sequence.
    
   0.763
H3CXQ0_TETNG
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.746
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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