Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3BYI0_TETNGCyclase associated actin cytoskeleton regulatory protein 2. (176 aa)    
Predicted Functional Partners:
H3CUV6_TETNG
Cyclase associated actin cytoskeleton regulatory protein 2.
 
     0.921
WDR1
WD repeat domain 1.
   
 
 0.850
H3DE68_TETNG
Glutaredoxin and cysteine rich domain containing 1 a.
    
   0.766
H3C528_TETNG
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 0.765
H3DHD8_TETNG
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.765
H3D7L7_TETNG
BAF chromatin remodeling complex subunit BCL7A.
    
   0.750
H3DB10_TETNG
Twinfilin actin-binding protein 2b.
   
 
 0.740
H3DEX6_TETNG
Twinfilin actin-binding protein 1a.
   
 
 0.740
H3DAY9_TETNG
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.705
Q4TA25_TETNG
Profilin; Belongs to the profilin family.
   
 0.574
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (18%) [HD]