Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3BYT9_TETNGHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)    
Predicted Functional Partners:
H3CA73_TETNG
AT rich interactive domain 4A (RBP1-like).
    
 0.848
H3DGW8_TETNG
Translocase of outer mitochondrial membrane 20.
    
 0.848
H3DHR2_TETNG
Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG.
    
 0.787
POLR2E
Chromosome 1 SCAF14751, whole genome shotgun sequence.
    
  0.763
Q4SF14_TETNG
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.760
Q4S7A1_TETNG
Chromosome 1 SCAF14716, whole genome shotgun sequence.
    
  0.752
Q4RGY9_TETNG
Chromosome undetermined SCAF15083, whole genome shotgun sequence.
   
 0.729
Q4S925_TETNG
Chromosome undetermined SCAF14702, whole genome shotgun sequence; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
   
  0.722
H3D6D6_TETNG
Deacetylase sirtuin-type domain-containing protein.
   
 0.721
H3DK21_TETNG
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
    
 0.712
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.