close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H3BYW0_TETNG1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1273 aa)    
Predicted Functional Partners:
H3CSB9_TETNG
Receptor protein-tyrosine kinase.
    
 0.947
H3CYP8_TETNG
Phosphoinositide phospholipase C.
     
0.925
H3DBV7_TETNG
Phosphoinositide phospholipase C.
     
0.925
H3C8V0_TETNG
PI3K-RBD domain-containing protein; Belongs to the PI3/PI4-kinase family.
    
 0.922
H3CXW1_TETNG
Uncharacterized protein.
    
0.920
H3CQL3_TETNG
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.916
H3DD14_TETNG
PIPK domain-containing protein.
     
 0.916
H3DD95_TETNG
Phosphatidylinositol-4-phosphate 5-kinase, type I, beta b.
     
 0.916
H3DIW8_TETNG
Kinase; Belongs to the inositol phosphokinase (IPK) family.
     
 0.916
Q4TJA1_TETNG
Chromosome undetermined SCAF335, whole genome shotgun sequence.
     
  0.915
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: medium (42%) [HD]