Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3BYZ9_TETNG3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1; Belongs to the 14-3-3 family. (247 aa)    
Predicted Functional Partners:
YWHAE
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
   
  0.928
H3D9W4_TETNG
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
   
  0.928
H3C7K4_TETNG
AKT1 substrate 1 (proline-rich).
   
 0.854
H3C0G6_TETNG
TSC complex subunit 2.
    
 0.835
H3CP98_TETNG
MDM4 regulator of p53; Belongs to the MDM2/MDM4 family.
    
 
 0.831
H3DNY5_TETNG
Yes-associated protein 1.
    
 0.822
SNCA
Synuclein alpha; Belongs to the synuclein family.
    
 
 0.814
CDC25B
Cell division cycle 25B.
    
 0.789
Q4RTW8_TETNG
Chromosome 12 SCAF14996, whole genome shotgun sequence.
   
 0.750
H3CXQ0_TETNG
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.745
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.