Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3BZ77_TETNGV-ski avian sarcoma viral oncogene homolog a. (318 aa)    
Predicted Functional Partners:
H3DBR4_TETNG
SKI-like proto-oncogene a.
    
  0.949
H3CC01_TETNG
Mothers against decapentaplegic homolog.
    
 0.909
H3CHE5_TETNG
Mothers against decapentaplegic homolog.
    
 0.909
H3CUH4_TETNG
Mothers against decapentaplegic homolog.
    
 0.909
SKI
Chromosome undetermined SCAF10501, whole genome shotgun sequence.
 
      0.899
HDAC3
Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (By similarity). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). Histone deacetylases act via the formation of large multiprotein complexes (By similarity). May play a role in the regulation of the circadian clock in a deacetylase activity-independent manner (By similarity).
    
 
 0.889
H3CWE6_TETNG
SNW domain containing 1.
    
 
 0.807
H3CDB0_TETNG
Nuclear receptor corepressor 2.
   
 0.801
H3CSZ3_TETNG
Nuclear receptor corepressor 1.
   
 0.801
H3DQN4_TETNG
Uncharacterized protein.
   
 0.801
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (12%) [HD]