Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (175 aa)    
Predicted Functional Partners:
H3D7K2_TETNG
Enolase-phosphatase 1.
 
  
 0.892
H3CW42_TETNG
APAF1 interacting protein.
 
  
 0.788
H3DH93_TETNG
Adducin 2 (beta).
  
  
 0.728
H3CVK3_TETNG
Trafficking protein particle complex 2-like.
    
   0.677
MRI1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.672
Q4RZR9_TETNG
Chromosome 18 SCAF14786, whole genome shotgun sequence.
    
   0.631
H3CC89_TETNG
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.593
H3BWK4_TETNG
Uncharacterized protein.
  
  
 0.542
H3CPY9_TETNG
Adducin 1 (alpha).
  
  
 0.542
H3CZ14_TETNG
Adducin 3 (gamma) a.
  
  
 0.542
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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