Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3BZL5_TETNGAP-1 complex subunit gamma. (829 aa)    
Predicted Functional Partners:
H3DEJ4_TETNG
AP complex subunit beta.
   
0.993
H3CG10_TETNG
AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
   
 0.990
H3DL57_TETNG
Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family.
   
 0.990
H3C362_TETNG
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.983
H3CVT5_TETNG
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.983
H3D9Y0_TETNG
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.983
H3DCU7_TETNG
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.983
H3D0I8_TETNG
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 0.974
H3DFM5_TETNG
Synergin, gamma.
   
 0.966
H3CQC6_TETNG
AP complex subunit beta.
   
0.958
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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