Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (219 aa)    
Predicted Functional Partners:
H3CTK3_TETNG
Trans-2,3-enoyl-CoA reductase-like 2a.
   
 0.758
Q4SE12_TETNG
Chromosome 3 SCAF14626, whole genome shotgun sequence.
   
 0.758
H3D9A8_TETNG
Trans-2,3-enoyl-CoA reductase b.
   
 0.758
Q4T9N8_TETNG
Chromosome undetermined SCAF7519, whole genome shotgun sequence; Belongs to the SKP1 family.
    
 
 0.681
H3CHL3_TETNG
Focadhesin.
      
 0.675
H3CW40_TETNG
Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.597
H3CYF6_TETNG
Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.597
Q4T1F0_TETNG
Chromosome 12 SCAF10644, whole genome shotgun sequence; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.581
H3D2I3_TETNG
Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.581
H3DP96_TETNG
Hydroxysteroid dehydrogenase like 1.
   
 0.581
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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