Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (284 aa)    
Predicted Functional Partners:
H3DE10_TETNG
M-phase phosphoprotein 8.
    
 0.768
H3D5Y7_TETNG
X-ray repair complementing defective repair in Chinese hamster cells 6.
    
 
 0.751
H3DD00_TETNG
Sirtuin 6.
  
 
 0.748
Q4RGF0_TETNG
Chromosome 18 SCAF15100, whole genome shotgun sequence.
    
 0.717
H3CTD1_TETNG
Cell division cycle and apoptosis regulator 1.
    
 0.687
H3D971_TETNG
Sirtuin 7.
  
 
 0.687
H3CFG2_TETNG
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
    
 
 0.655
H3BZT2_TETNG
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
   
 
 0.647
cyc
Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (By similarity).
   
 
 0.647
H3BXG6_TETNG
CPSase_sm_chain domain-containing protein.
  
 0.640
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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