Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
H3C061_TETNGUncharacterized protein. (49 aa)    
Predicted Functional Partners:
H3D1U5_TETNG
MOB family member 4, phocein.
    
 
 0.882
H3BWS6_TETNG
Sarcolemma associated protein a.
    
 
 0.877
H3DII8_TETNG
Programmed cell death 10b.
    
 
 0.866
H3CCT7_TETNG
Protein phosphatase 2, regulatory subunit A, beta b.
    
 
 0.818
H3CWR5_TETNG
FGFR1 oncogene partner 2.
    
 
 0.804
Q4T615_TETNG
Chromosome 9 SCAF8987, whole genome shotgun sequence.
    
 
 0.771
H3CNK4_TETNG
CTTNBP2 N-terminal like a.
    
 
 0.771
RNF8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
    
 
 0.769
H3CGL5_TETNG
WD_REPEATS_REGION domain-containing protein.
   
 
 0.762
STRN
Striatin.
   
 
 0.762
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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