Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3C077_TETNGThromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family. (537 aa)    
Predicted Functional Partners:
PTGS1
Prostaglandin-endoperoxide synthase 1.
   
 
 0.950
H3CPX4_TETNG
Prostaglandin E synthase.
     
 0.948
H3DH42_TETNG
Prostaglandin E synthase 2-like.
     
 0.945
H3DCB2_TETNG
Prostaglandin E synthase 3a (cytosolic).
   
 
 0.924
H3CM47_TETNG
Uncharacterized protein; Belongs to the cytochrome P450 family.
     
 0.919
PTGIS
Prostaglandin I2 synthase; Belongs to the cytochrome P450 family.
     
0.919
H3DB79_TETNG
Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family.
     
 0.919
H3DL92_TETNG
Prostaglandin-endoperoxide synthase 2b.
     
 0.918
H3DBD7_TETNG
Peroxiredoxin like 2B.
     
 0.904
H3CRS6_TETNG
Prostaglandin D2 synthase b, tandem duplicate 1; Belongs to the calycin superfamily. Lipocalin family.
     
  0.900
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
Server load: low (38%) [HD]