Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
H3C0A4_TETNGUncharacterized protein. (721 aa)    
Predicted Functional Partners:
H3D9S4_TETNG
Uncharacterized protein.
 
  
   0.632
H3CPF5_TETNG
Macrophage stimulating 1 receptor b.
    
 0.560
H3DB91_TETNG
Macrophage stimulating 1 receptor a.
    
 0.560
H3DF54_TETNG
MET proto-oncogene, receptor tyrosine kinase.
    
 0.560
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
    
 
 0.534
H3CAN7_TETNG
Ribosome production factor 2 homolog.
   
 
 0.532
H3C1G4_TETNG
Lumican.
    
 0.529
H3DLH4_TETNG
Sprouty homolog 4 (Drosophila).
    
 0.509
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
 
 0.504
H3CKT9_TETNG
Contactin 2.
    
 
 0.498
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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