Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H3C0G2_TETNGPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (179 aa)    
Predicted Functional Partners:
H3D9P7_TETNG
Platelet-derived growth factor receptor, beta polypeptide.
   
 0.971
H3BZA2_TETNG
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
   
 0.906
H3D592_TETNG
Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.886
H3CI46_TETNG
Platelet derived growth factor d; Belongs to the PDGF/VEGF growth factor family.
     
 0.783
H3D673_TETNG
Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
     
 0.768
H3DKT6_TETNG
Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.
    
 0.697
H3DND0_TETNG
Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.
    
 0.697
H3CV79_TETNG
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
   
 
  0.553
H3D3P2_TETNG
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
   
 
  0.553
H3D2C0_TETNG
Signal transducer and activator of transcription.
     
 0.543
Your Current Organism:
Tetraodon nigroviridis
NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish
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